HA injections improve knee OA symptoms and may exert a 1-year carry-over effect

Ann Rheum Dis. 2011 Nov;70(11):1957-62.

HA more effective than placebo in knee OA, no difference between 3 and 6 injections of HA

. 2006 ;():.

Both PRP and HA injections improve pain and function in early knee OA compared to saline

Knee Surg Sports Traumatol Arthrosc. 2017 Mar;25(3):958-965

HA injections effective in improving pain & function in patients with knee osteoarthritis

Clin Rheumatol. 2005 Aug;24(4):336-41. Epub 2004 Dec 14

Hyaluronic acid injections for knee osteoarthritis have similar effect to placebo

Minerva Med. 2010 Apr;101(2):63-72.

ISAKOS: Similiar Results with PRP and HA Injections for Early Knee Osteoarthritis

Multi-injection HA appears to be more effective than single-injection HA versus saline for knee OA

BMC Musculoskelet Disord. 2017 Dec 21;18(1):542

HA injections successful in improving pain and function in knee osteoarthritis patients

The Pain Clinic, Vol. 15, No. 4, pp. 459–466 (2003)

AOSSM: PRP and HA produce similar clinical outcomes treating chondropathy or early knee OA

IA-HA injection as adjunct to microfracture surgery for osteochondral lesions of the talus

Knee Surg Sports Traumatol Arthrosc. 2016 Apr;24(4):1243-9

Efficacy of hyaluronic acid versus steroid injection for patients with trigger finger

Arch Phys Med Rehabil. 2015 Dec;96(12):2120-7

Knee OA: Intraarticular injections of PRP show no benefit over HA over a 12 month period

Am J Sports Med. 2015 Jul;43(7):1575-82

Autologous PRP vs. HA injections for pain, function, activity improvement in knee OA

Int J Mol Sci. 2016 Jul 2;17(7).

Efficacy and safety of five weekly HA vs placebo injections in the treatment of knee OA

J Rheumatol. 2004 Apr;31(4):775-82.

Ankle OA: 3 weekly injections of 1 mL hyaluronic acid reduces ankle joint pain

Foot Ankle Surg. 2010 Dec;16(4):159-63. doi: 10.1016/j.fas.2009.10.003. Epub 2009 Nov 8

AAOS 2015: Platelet-rich plasma vs hyaluronic acid for knee osteoarthritis

Intra-articular high-molecular weight HA injections similar to placebo in knee OA

Clin Exp Rheumatol. 2001 May-Jun;19(3):265-70

AAOS2017: Intraarticular PRP vs HA injections for degenerative knee pathology

Intraarticular HA injections effective for muscle strength & pain in knee osteoarthritis

Osteoarthritis Cartilage. 2002 Sep;10(9):680-6

IA-PRP significantly better than HA or corticosteroid injections in function or pain in knee OA

Orthopade. 2019 Mar;48(3):239-247.