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Biophysical stimulation offers improved outcomes for talar osteochondral lesions

Foot Ankle Int. 2014 Oct;35(10):981-7.

RCT Foot & Ankle Lesion Lower Extremity Bone Talus Bone Marrow-Derived Cells Transplantation Control PEMF Pulsed Electromagnetic Fields Stimulation - Hide

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Assessing efficacy of allogeneic, bone marrow-derived mesenchymal stem cells in knee OA treatment

Arthritis Res Ther. 2016 Dec 20;18(1):301.

RCT Osteoarthritis Lower Extremity Knee Arthritis Allogeneic Bone Marrow-Derived Placebo Injection - Hide

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Intra-articular bone marrow-derived stem cell injection effective in high tibial osteotomy

Arthroscopy. 2013 Dec;29(12):2020-8. doi: 10.1016/j.arthro.2013.09.074

RCT Osteoarthritis Lower Extremity Knee Bone Tibia Arthritis Cartilage Arthroscopy Autologous Bone Marrow Injection Bone Marrow-Derived Cell-Recipient Control HA Hyaluronic Acid Microfracture Standard Medial Opening High-Tibial Osteotomy Mesenchymal Stem Cells - Hide

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No difference in function between stem cells and control during microfracture

Regen Ther. 2019;(11):106-113. doi: 10.1016/j.reth.2019.06.002

RCT Sports Medicine Lesion Lower Extremity Knee Cartilage Autologous Bone Marrow Bone Marrow-Derived Control Microfracture Mesenchymal Stem Cells - Hide

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Bone-marrow derived stem cells contribute significantly to neuro-recovery in spinal cord injuries

Asian J Transfus Sci. 2019 ;():. 10.4103/ajts.AJTS_44_18.

RCT Spine Axial Skeleton Conservative Management Physical Therapy Surgery Surgery Lumbar Spine Spinal cord injury and/or disease Bone Marrow-derived Mononuclear Cells Spine stabilization - Hide

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Adult stem cells do not appear to accelerate graft-to-bone healing in ACL reconstruction

Knee Surg Sports Traumatol Arthrosc. 2014 Jan;22(1):66-71. doi: 10.1007/s00167-012-2279-9. Epub 2012 Nov 2.

RCT Sports Medicine Joint Ligament Muscle Hamstring Bone Marrow Control Graft Harvested Reconstruction Stem Cells - Hide

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Skin-derived tenocyte-like cells for patellar tendinopathy improves pain and function

Am J Sports Med. 2011 Mar;39(3):614-23. doi: 10.1177/0363546510387095. Epub 2010 Dec 7

RCT Sports Medicine Bone Patella Muscle Patellar Tendon Pain Tendinopathy Tendinosis Control Injection Of Autologous Plasma Ultrasound-Guided Injection - Hide

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Benefit of BM-MSC addition in core decompression in treatment of osteonecrosis of the femoral head

Int J Surg. 2019 Jul 10;69:23-31

Meta-analysis Sports Medicine Bone Femur Head Arthroplasty Autologous Bone Marrow-Derived Mesenchymal Stem Cell Control Core Decompression Impact Stem Cells - Hide

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Bone marrow injection further benefits core decompression treatment for osteonecrosis

J Arthroplasty. 2015 Sep;30(9 Suppl):11-5

RCT General Orthopaedics Lower Extremity Hip Bone Femur Head Autologous Bone Marrow Bone Marrow Injection Bone Marrow Stem Cell Concentrated Core Decompression - Hide

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AAOS 2015: Bone marrow augmentation in core decompression beneficial in treatment of ONFH

RCT General Orthopaedics Lower Extremity Hip Bone Femur Head Augmentation Injection Bone Marrow Concentrate Concentrated Core Decompression - Hide

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G-CSF based PBSC transplantation with biomechanical support is safe & effective in ONFH

J Bone Miner Res. 2015 Apr;30(4):647-56

RCT Osteoarthritis Lower Extremity Hip Bone Femur Head Arthritis Biomechanical Factor Peripheral Blood Stem Cells Porous Tantalum Rod Implantation Support Transplantation - Hide

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Hematopoietic stem cell transplantation: Improved QOL with physical exercise programs

Phys Ther. 2013 Apr;93(4):514-28. doi: 10.2522/ptj.20120181. Epub 2012 Dec 6.

Meta-analysis Physical Therapy & Rehab Bone Marrow Control Physical Exercise Program Physical Therapy Physiotherapy Psychological Training Transplantation - Hide

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Adipose-derived stem cells added to microfracture beneficial for knee cartilage lesions

Arthroscopy. 2016 Jan;32(1):97-109

RCT General Orthopaedics Lesion Lower Extremity Knee Cartilage Adscs Injection Fibrin Glue Microfracture Stem Cells - Hide

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Osteonecrosis of the hip: Autologous bone marrow mononuclear cell instillation

J Arthroplasty. 2012 May;27(5):679-86. Epub 2011 Oct 13

RCT Arthroplasty Lower Extremity Hip Bone Femur Head Autologous Bone Marrow Mononuclear Cell Control Core Decompression - Hide

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Intraarticular stem cell injection favoured over oral acetaminophen after 6-mo in knee OA treatment

Int J Rheum Dis. 2018 Jan;21(1):140-147. doi: 10.1111/1756-185X.13139

RCT Osteoarthritis Lower Extremity Knee Arthritis Pain Injection Bone Marrow Oral Acetaminophen Mesenchymal Stem Cells - Hide

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Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis

Adv Orthop. 2021 Nov 20;2021:2146722. doi: 10.1155/2021/2146722. eCollection 2021.. 2021 01-Nov;():. 10.1155/2021/2146722

RCT Osteoarthritis Appendicular Lower Extremity Knee NSAID Physical Therapy Biologic Biologic Non-selective NSAID Autologous Bone Marrow-Derived Chondrocytes - Hide

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Bone marrow concentrate implantation alongside decompression of no benefit in ONFH treatment

Int Orthop. 2018 Jul;42(7):1429-1435. doi: 10.1007/s00264-017-3650-8. Epub 2017 Oct 7

RCT General Orthopaedics Bone Femur Head Pharmacia Bone Marrow Concentrate Decompression - Hide

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Bone healing non-significantly longer with PRP bone substitute graft

Cartilage October 2010 vol. 1 no. 4 320-327

RCT General Orthopaedics Deformity Lower Extremity Knee Bone Iliac Tibia Autologous Iliac Bone Graft Autologous Iliac Graft Biological Graft Graft Of Bone Marrow Aspirate Platelet-Rich Plasma PRP Tibial Osteotomy - Hide

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Chondral lesions: MACT presents promising outcomes but higher-quality literature is needed

Bone Joint Res. 2013 Feb 1;2(2):18-25

Meta-analysis General Orthopaedics Lesion Lower Extremity Knee Cartilage ACI Assisted Autologous Chondrocyte Implantation Current Matrix Scaffold Transplantation - Hide

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High- and low-dose BM-MSC injection versus control for treatment of knee osteoarthritis

J Transl Med. 2016 Aug 26;14(1):246. doi: 10.1186/s12967-016-0998-2

RCT Osteoarthritis Lower Extremity Knee Arthritis Autologous Bone Marrow Injection Control High-Dose Hyaluronic Acid Low-Dose - Hide

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Biophysical stimulation offers improved outcomes for talar osteochondral lesions

Assessing efficacy of allogeneic, bone marrow-derived mesenchymal stem cells in knee OA treatment

Intra-articular bone marrow-derived stem cell injection effective in high tibial osteotomy

No difference in function between stem cells and control during microfracture

Bone-marrow derived stem cells contribute significantly to neuro-recovery in spinal cord injuries

Adult stem cells do not appear to accelerate graft-to-bone healing in ACL reconstruction

Skin-derived tenocyte-like cells for patellar tendinopathy improves pain and function

Benefit of BM-MSC addition in core decompression in treatment of osteonecrosis of the femoral head

Bone marrow injection further benefits core decompression treatment for osteonecrosis

AAOS 2015: Bone marrow augmentation in core decompression beneficial in treatment of ONFH

G-CSF based PBSC transplantation with biomechanical support is safe & effective in ONFH

Hematopoietic stem cell transplantation: Improved QOL with physical exercise programs

Adipose-derived stem cells added to microfracture beneficial for knee cartilage lesions

Osteonecrosis of the hip: Autologous bone marrow mononuclear cell instillation

Intraarticular stem cell injection favoured over oral acetaminophen after 6-mo in knee OA treatment

Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis

Bone marrow concentrate implantation alongside decompression of no benefit in ONFH treatment

Bone healing non-significantly longer with PRP bone substitute graft

Chondral lesions: MACT presents promising outcomes but higher-quality literature is needed

High- and low-dose BM-MSC injection versus control for treatment of knee osteoarthritis

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