In this celebratory 100th episode, co-hosts reflect on standout moments from the OrthoJoe podcast, highlighting game-changing conversations on AI in medicine, diversity in orthopedics, physician attire, and the power of the humanities in healthcare. From discussions with pioneers like Clarence Shields to explorations of generational change and landmark studies, this episode captures the podcast’s rich legacy of insight, humor, and human connection—offering a compelling look at how far the field has come and what lies ahead.