ChatGPT is framed as a transformative but imperfect tool, one that generates convincingly human answers without actually knowing truth. The discussion highlights how it differs from Google, how it learns patterns from vast text corpora, and why it can still “hallucinate.” The hosts explore implications for healthcare—diagnosis, documentation, patient education—and caution that AI will augment rather than replace clinicians, though some tasks may inevitably shift. Broader reflections follow on tech companies pushing tools into healthcare, the need for high-quality interoperable data, and the risk of forcing solutions onto problems rather than addressing foundational system gaps. Fast Five topics cover long-term outcomes in open tibial fractures, nail diameter debates, regenerative injectables including MSC–PRP combinations, and a sports-medicine segment on Patrick Mahomes’ high-ankle injury. The tone blends curiosity with pragmatism: AI offers real promise but demands careful, evidence-based integration.