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Comparison of efficacy and safety of two single injection hyaluronic acid preparations for knee OA
January 2018
Comparison of efficacy and safety of two single injection hyaluronic acid preparations for knee OA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Comparison of Single Intra-Articular Injection of Novel Hyaluronan (HYA-JOINT Plus) with Synvisc-One for Knee Osteoarthritis: A Randomized, Controlled, Double-Blind Trial of Efficacy and Safety
J Bone Joint Surg Am. 2017 Mar 15;99(6):462-471Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
132 patients with mild-to-moderate, symptomatic knee osteoarthritis were randomized to a single injection of either HYA-JOINT Plus (SciVision Biotech) or Synvisc-One (Sanofi-Aventis). Patients were assessed over a 6-month follow-up for patient-reported outcome measures, functional performance measures, patient satisfaction, and rate of adverse events. Pain assessed using a visual analog scale was ...
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