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Topical NSAIDs demonstrate significant reduction in pain versus placebo for treatment of knee OA
August 2017
Topical NSAIDs demonstrate significant reduction in pain versus placebo for treatment of knee OA
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A
Longterm efficacy of topical nonsteroidal antiinflammatory drugs in knee osteoarthritis: metaanalysis of randomized placebo controlled clinical trials
J Rheumatol. 2006 Sep;33(9):1841-4Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Four randomized controlled trials were included in this meta-analysis comparing the efficacy of topical non-steroidal anti-inflammatory drug (NSAID) therapy to placebo in the treatment of knee osteoarthritis. Pain scores were significantly lower with the use of topical NSAIDs compared to placebo at follow-up ranging from 4-12 weeks.
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