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Prolonged use of corticosteroid injections for knee osteoarthritis reduces cartilage volume
May 2017
Prolonged use of corticosteroid injections for knee osteoarthritis reduces cartilage volume
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients With Knee Osteoarthritis: A Randomized Clinical Trial.
JAMA. 2017 May 16;317(19):1967-1975Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
140 patients with symptomatic knee osteoarthritis (Kellgren-Lawrence grade II-III) and ultrasonographic evidence of synovitis were included in this trial to determine the effects of prolonged corticosteroid use on cartilage loss and pain. Patients were randomized to injections of triamcinolone acetonide or saline every 12 weeks for a period of two years. The outcomes assessed included cartilage lo...
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