Efficacy and safety of newer anticoagulants vs enoxaparin for thromboprophylaxis after TJA
Safety and Efficacy of New Anticoagulants for the Prevention of Venous Thromboembolism After Hip and Knee Arthroplasty: A Meta-AnalysisJ Arthroplasty. 2017 Feb;32(2):645-652
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18 randomized controlled trials were included in this meta-analysis evaluating the efficacy and safety of newer anticoagulants compared to enoxaparin in total knee and total hip arthroplasty. Anticoagulants evaluated included apixaban, dabigatran, fondaparinux, rivaroxaban, and edoxaban. The only newer anticoagulant which failed to demonstrate a significant reduction in VTE incidence relative to e...
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