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Zoledronic Acid, alendronate, and risedronate reduce vertebral, nonvertebral, and hip fracture
October 2018
Zoledronic Acid, alendronate, and risedronate reduce vertebral, nonvertebral, and hip fracture
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A
Comparative efficacy of bisphosphonates in short-term fracture prevention for primary osteoporosis: a systematic review with network meta-analyses
Osteoporos Int. 2016 Nov;27(11):3289-3300Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
36 randomized controlled trials were included in this network meta-analysis to evaluate the comparative efficacy of different bisphosphonates in the management of osteoporosis. Nine different bisphosphonates were assessed in the included studies, with direct and indirect comparisons evaluated for vertebral fracture, nonvertebral fracture, hip fracture, wrist fracture, and any fracture. Zoledronic ...
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