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Repeat IV-TXA at 3 & 6hrs reduces hidden blood loss compared to preop dose alone in TKA
May 2017
Repeat IV-TXA at 3 & 6hrs reduces hidden blood loss compared to preop dose alone in TKA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Multiple Boluses of Intravenous Tranexamic Acid to Reduce Hidden Blood Loss After Primary Total Knee Arthroplasty Without Tourniquet: A Randomized Clinical Trial
J Arthroplasty. 2016 Nov;31(11):2458-2464Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
151 patients undergoing total knee arthroplasty were included in this randomized trial to evaluate the efficacy of different intravenous tranexamic acid administration protocols for reducing hidden blood loss. Patients were randomized into 3 groups: Group A (control) received intravenous (IV) TXA pre-op and IV placebo at 3 and 6 hours. Group B (3h TXA) received IV TXA pre-op and at 3 hours, and IV...
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