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Volume:5 Issue:6 Number:7 ISSN#:2563-5476
RCT
ACE Report #9386
Ace Report Cover Spine

Efficacy of vertebroplasty vs sham for acute vertebral fracture in patients over 60


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Safety and efficacy of vertebroplasty for acute painful osteoporotic fractures (VAPOUR): a multicentre, randomised, double-blind, placebo-controlled trial

Lancet. 2016 Oct 1;388(10052):1408-1416

Contributing Authors: TH Diamond C Bryant W Clark P Bird P Gonski P Smerdely HP McNeil G Schlaphoff E Barnes V Gebski

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Synopsis

120 patients over the age of 60 with an acute vertebral fracture were randomized to undergo either vertebroplasty or a sham procedure designed to simulate vertebroplasty. The purpose of this study was to compare patient-reported pain, disability and quality of life over 14-day and 6-month follow-ups. Results demonstrated significant between-group differences in favour of the vertebroplasty group i...

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