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Short- and long-course levofloxacin plus rifampicin for prosthetic joint infection

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Ace Report Cover
January 2017

Short- and long-course levofloxacin plus rifampicin for prosthetic joint infection

Vol: 6| Issue: 1| Number:20| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Short- versus long-duration levofloxacin plus rifampicin for acute staphylococcal prosthetic joint infection managed with implant retention: a randomised clinical trial

Int J Antimicrob Agents. 2016 Sep;48(3):310-6

Contributing Authors:
J Lora-Tamayo G Euba J Cobo JP Horcajada A Soriano E Sandoval C Pigrau N Benito L Falgueras J Palomino Del Toro A Jover-Sáenz JA Iribarren M Sánchez-Somolinos A Ramos M Fernández-Sampedro M Riera JM Baraia-Etxaburu J Ariza Prosthetic

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Synopsis

63 patients with a hip or knee prosthetic joint infection by either Staphylococcus aureus or coagulase-negative staphylococci were randomized to either 8 weeks of levofloxacin and rifampicin following debridement, or 3- and 6-months levofloxacin and rifampicin following debridement (3 months for hip infection and 6 months for knee infection). The purpose of this study was to compare infection cure...

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