Network meta-analysis of anti-osteoporosis therapies for oral glucocorticoid users

Study Type:Meta-analysis/Systematic Review

OE Level Evidence:2

Journal Level of Evidence:N/A

Efficacy of osteoporosis pharmacotherapies in preventing fracture among oral glucocorticoid users: a network meta-analysis

Osteoporos Int. 2016 Jun;27(6):1989-98

Contributing Authors: MA Amiche JM Albaum M Tadrous P Pechlivanoglou LE Lévesque JD Adachi SM Cadarette

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

Synopsis

27 randomized controlled trials that examined 9 different active treatments were included in this network meta-analysis to evaluate the efficacy of various treatments compared to placebo plus calcium and vitamin D in the treatment of patients with glucocorticoid-induced osteoporosis. Outcomes assessed in this network meta-analysis were incidence of vertebral fractures, incidence of non-vertebral f...