Efficacy of zoledronic acid following PLIF in patients with osteoporosis

How to Cite

OrthoEvidence. Efficacy of zoledronic acid following PLIF in patients with osteoporosis. ACE Report. 2017;6(2):47. Available from: https://myorthoevidene.com/AceReport/Report/8941

Study Type:Therapy

OE Level Evidence:2

Journal Level of Evidence:N/A

Effects of zoledronic acid on bone fusion in osteoporotic patients after lumbar fusion

Osteoporos Int. 2016 Apr;27(4):1469-76

Contributing Authors: F Chen Z Dai Y Kang G Lv ET Keller Y Jiang

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

Synopsis

79 patients with osteoporosis scheduled for instrumented posterior lumbar interbody fusion due to single-level degenerative spondylolisthesis were randomized to be postoperatively administered either zoledronic acid or saline. The purpose of this study was to compare groups based on fusion status, the incidence of a subsequent vertebral compression fracture, clinical outcome, serum biomarkers of b...