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Efficacy of zoledronic acid following PLIF in patients with osteoporosis
February 2017
Efficacy of zoledronic acid following PLIF in patients with osteoporosis
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Effects of zoledronic acid on bone fusion in osteoporotic patients after lumbar fusion
Osteoporos Int. 2016 Apr;27(4):1469-76Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
79 patients with osteoporosis scheduled for instrumented posterior lumbar interbody fusion due to single-level degenerative spondylolisthesis were randomized to be postoperatively administered either zoledronic acid or saline. The purpose of this study was to compare groups based on fusion status, the incidence of a subsequent vertebral compression fracture, clinical outcome, serum biomarkers of b...
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