Efficacy of zoledronic acid following PLIF in patients with osteoporosis
Effects of zoledronic acid on bone fusion in osteoporotic patients after lumbar fusionOsteoporos Int. 2016 Apr;27(4):1469-76
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79 patients with osteoporosis scheduled for instrumented posterior lumbar interbody fusion due to single-level degenerative spondylolisthesis were randomized to be postoperatively administered either zoledronic acid or saline. The purpose of this study was to compare groups based on fusion status, the incidence of a subsequent vertebral compression fracture, clinical outcome, serum biomarkers of b...