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Ace Report Cover

No beneficial effects of oral vitamin D3 on cartilage volume or knee pain in knee OA

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Ace Report Cover
June 2016

No beneficial effects of oral vitamin D3 on cartilage volume or knee pain in knee OA

Vol: 5| Issue: 6| Number:41| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis A Randomized Clinical Trial

JAMA. 2016 Mar 8;315(10):1005-13

Contributing Authors:
X Jin G Jones F Cicuttini A Wluka Z Zhu W Han B Antony X Wang T Winzenberg L Blizzard C Ding

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Synopsis

413 patients with knee osteoarthritis and low vitamin D levels were randomized to a monthly treatment of either oral vitamin D3 or an identical placebo for 24 months. The purpose of this study was to determine whether or not vitamin D supplements are beneficial in mitigating knee pain and improving knee cartilage volume, when compared with placebo up to 2 years. Findings indicated no significant d...

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