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No beneficial effects of oral vitamin D3 on cartilage volume or knee pain in knee OA
June 2016
No beneficial effects of oral vitamin D3 on cartilage volume or knee pain in knee OA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Effect of Vitamin D Supplementation on Tibial Cartilage Volume and Knee Pain Among Patients With Symptomatic Knee Osteoarthritis A Randomized Clinical Trial
JAMA. 2016 Mar 8;315(10):1005-13Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
413 patients with knee osteoarthritis and low vitamin D levels were randomized to a monthly treatment of either oral vitamin D3 or an identical placebo for 24 months. The purpose of this study was to determine whether or not vitamin D supplements are beneficial in mitigating knee pain and improving knee cartilage volume, when compared with placebo up to 2 years. Findings indicated no significant d...
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