
OARSI 2016: Exercise + dietary weight loss influence on inflammatory biomarkers in knee OA

OARSI 2016: Exercise + dietary weight loss influence on inflammatory biomarkers in knee OA
Effects of exercise and weight loss on interstitial matrix turnover and tissue inflammation biomarkers in adults with knee osteoarthritis: the intensive diet and exercise for arthritis trial (IDEA)
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Synopsis
454 overweight/obese patients with knee OA were randomized to one of three interventions for the purpose of determining if any treatment was associated with significantly decreased the serum concentration of specific inflammatory biomarkers after 18 months: (1) Diet only, (2) Diet and Exercise, and (3) Exercise only intervention. Results demonstrated that a significant reduction of C1M and C3M wer...
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