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AAOS 2016: TXA vs. epsilon-aminocaproic acid provide comparable outcomes after TKA

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Ace Report Cover
March 2016

AAOS 2016: TXA vs. epsilon-aminocaproic acid provide comparable outcomes after TKA

Vol: 5| Issue: 3| Number:58| ISSN#: 2564-2537
Study Type:Randomized Trial
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Tranexamic Acid and Epsilon-Aminocaproic Acid to Reduce Blood Loss Following Total Knee Arthroplasty

Contributing Authors:
CK Boese L Centeno M Weis R Walters R Baker MJ Harris B Cooley TJ Gallo

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CONFERENCE ACE REPORTS

This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.

Synopsis

140 patients scheduled for total knee arthroplasty (TKA) were randomized to be administered either tranexamic acid or epsilon-aminocaproic acid. The purpose of this study was to compare the antifibrolytic effects of the two drugs after total knee arthroplasty. Findings indicated no significant differences in transfusion rates, drop in haemoglobin (Hb) levels, serum creatinine change, and postopera...

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