ACE Report #8673
Ace Report Cover Arthroplasty

AAOS 2016: Intravenous and topical TXA yield similar efficacy and safety in THA

Study Type:Meta analysis
OE Level Evidence:N/A
Journal Level of Evidence:N/A

Tranexamic Acid in Total Hip Arthroplasty: Do Drug Formulation and Dosage Determine Efficacy and Safety?

Contributing Authors: Y Fillingham JC Riboh B Erickson GL Cvetanovich CJ Della Valle

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This ACE Report is a summary of a conference presentation or abstract. The information provided has limited the ability to provide an accurate assessment of the risk of bias or the overall quality. Please interpret the results with caution as trials may be in progress and select results may have been presented.


19 randomized controlled trials (RCTs) with a total of 1,388 patients were included in this network meta-analysis. The object of this analysis was to determine the effectiveness of various tranexamic acid (TXA) formulations in total hip arthroplasty (THA) patients). Findings indicated more significant reduction in transfusion rate and blood loss with intravenous tranexamic acid, either as a low-do...

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