AAOS 2016: IV+IA TXA significantly reduces blood loss compared to IV TXA alone in TKA
Combined Intra-Articular and Intravenous Tranexamic Acid Significantly Reduce Blood Loss in Knee Arthroplasty
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60 patients undergoing total knee arthroplasty were randomized to receive either both intravenous (IV) and intra-articular (IA) tranexamic acid administration, or intravenous administration alone. The study was conducted in order to determine whether the addition of IA TXA to IV TXA was associated with a significant reduction in total blood loss. Findings indicated that the combined administration...
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