Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
ACE Report #8490
Ace Report Cover General Orthopaedics

Hyaluronic acid more effective versus methylprednisolone in the long term for knee OA

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Intra-articular treatment of osteoarthritis of the knee: an arthroscopic and clinical comparison between sodium hyaluronate (500-730 kDa) and methylprednisolone acetate

J Orthopaed Traumatol (2002) 3:89–96

Contributing Authors: L Frizziero IP Ronchetti

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here


99 patients with knee osteoarthritis (OA) were randomized to treatment with either hyaluronic acid (HA) or methylprednisolone acetate (MP) and followed up for 180 days. The purpose of this study was to determine the clinical efficacy and the structural effects of the two intra-articular injections. MP showed lower pain scores compared to HA initially following injection up to 35 days, although the...

To view the full report, start your 30-day free trial today

No credit card required

JOIN Forgot Password?

Not sure if you want to join OrthoEvidence?

Access this report without an Account.

Success, an email containing a link to access this report has been sent to your inbox.

CME Image

Continuing Medical Education Credits

You could be earning 0.5 CME credits for each report you read.


Please Login or Join to leave comments.