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Results from randomized controlled trials in spine surgery frequently fragile

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Ace Report Cover
January 2016

Results from randomized controlled trials in spine surgery frequently fragile

Vol: 5| Issue: 1| Number:70| ISSN#: 2564-2537
Study Type:Systematic review
OE Level Evidence:N/A
Journal Level of Evidence:N/A

The fragility of statistically significant findings from randomized trials in spine surgery: a systematic survey

Spine J. 2015 Oct 1;15(10):2188-97

Contributing Authors:
M Bhandari M Walsh C Smith G Guyatt PJ Devereaux N Evaniew M Ghert C Files

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Synopsis

Results from 40 randomized controlled trials investigating interventions in spine surgery were included in this study. This review aimed to apply the recently described Fragility Index to statistically significant dichotomous outcomes in order to examine the robustness of these results. The median Fragility Index was 2 (IQR 1-3), indicating that the changing of a non-event into an event in only a ...

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