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Efficacy of three hyaluronic acid dosing strategies in the treatment of knee OA

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Ace Report Cover
January 2016

Efficacy of three hyaluronic acid dosing strategies in the treatment of knee OA

Vol: 5| Issue: 1| Number:26| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

The Safety and Efficacy of Different Dose Schedules of Hyaluronic Acid in the Treatment of Painful Osteoarthritis of the Knee with Joint Effusion

Eur J Rheumatol Inflamm. 1995 Jan;15(1):25-31

Contributing Authors:
M Carrabba E Paresce M Angelini KA Re EEM Torchiana A Perbellini

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Synopsis

100 participants with knee osteoarthritis and joint effusion were randomized into one of 5 groups. The purpose of the study was to evaluate and compare clinical results of three different dosing schedules - 1, 3, or 5 weekly injections - of intra-articualr hyaluronic acid, to that of placebo treatment and control arthrocentesis. Outcomes of interest included pain at rest, pain during motion, funct...

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