
TXA effective in reducing blood loss and transfusion in TKA vs. routine hemostasis

TXA effective in reducing blood loss and transfusion in TKA vs. routine hemostasis
Topical and intravenous tranexamic acid reduce blood loss compared to routine hemostasis in total knee arthroplasty: a multicenter, randomized, controlled trial
Arch Orthop Trauma Surg. 2015 Jul;135(7):1017-25Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
150 patients undergoing primary total knee arthroplasty (TKA) were randomized to receive 1 g of topical tranexamic acid (TXA), 2 g of intravenous TXA, or routine hemostasis. The purpose of the study was to determine which TXA administration modality more effectively reduced total blood loss 24 post-surgery and the need for subsequent blood transfusions. Findings indicated that although a significa...
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