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ACE Report #7754
Ace Report Cover Spine

Pilot study on B2A shows comparable results to ICBG in lumbar spine fusion


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Twelve-month results of a multicenter, blinded, pilot study of a novel peptide (B2A) in promoting lumbar spine fusion

J Neurosurg Spine. 2015 Apr;22(4):358-66.

Contributing Authors: Z Sardar D Alexander W Oxner Plessis Sd A Yee EK Wai DG Anderson P Jarzem

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Synopsis

24 patients were included in this blinded, pilot, randomized clinical trial to evaluate a novel synthetic peptide, B2A, combined with ceramic granules and local bone autograft. Patients were randomized into one of three groups; either B2A at differing concentrations (750 or 150) combined with ceramic granules and local bone autograft at, or to iliac crest bone grafting. The results of this trial o...

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