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Author Verified
Meta-analysis
ACE Report #7729
Ace Report Cover Spine

TXA efficacy in perioperative spinal surgery bleeding


Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Efficacy of tranexamic acid on surgical bleeding in spine surgery: a meta-analysis

Spine J. 2015 Apr 1;15(4):752-761.

Contributing Authors: T Cheriyan Maier SP 2nd K Bianco K Slobodyanyuk RN Rattenni V Lafage FJ Schwab BS Lonner TJ Errico

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Synopsis

This meta-analysis included 11 randomized trials that investigated the effectiveness of intravenous tranexamic acid (TXA) in blood loss reduction during spinal surgery in comparison to a placebo or no treatment group. A total of 644 patients were included from the 11 studies. Pooling of the data found that TXA reduced intraoperative, postoperative, and total blood loss compared to control groups. ...

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