
TXA efficacy in perioperative spinal surgery bleeding

June 2015
TXA efficacy in perioperative spinal surgery bleeding
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A
Efficacy of tranexamic acid on surgical bleeding in spine surgery: a meta-analysis
Spine J. 2015 Apr 1;15(4):752-761.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
This meta-analysis included 11 randomized trials that investigated the effectiveness of intravenous tranexamic acid (TXA) in blood loss reduction during spinal surgery in comparison to a placebo or no treatment group. A total of 644 patients were included from the 11 studies. Pooling of the data found that TXA reduced intraoperative, postoperative, and total blood loss compared to control groups. ...
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