Intra-articular hyaluronic acid provides longer pain relief as compared to corticosteroid .
Intra-articular hyaluronic acid and corticosteroids in the treatment of knee osteoarthritis: A meta‑analysis
Exp Ther Med. 2015 Feb;9(2):493-500.7 randomized controlled trials (RCTs) were included in this meta-analysis comparing the effect of intra-articular hyaluronic acid (HA) injections and corticosteroids (CS) for the treatment of knee osteoarthritis (OA). Visual analog scale (VAS), Lequesne index, Knee Society Clinical Rating System (KSS), maximum flexion, and adverse events of treatments were measured. Analysis revealed that VAS scores between the two groups at one month were similar, but at 3 and 6 months, hyaluronic acid injections provided greater pain relief. The other measured clinical outcomes were similar between groups.
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