Topical TXA reduces transfusion and blood loss in THA compared to placebo
Topical application of tranexamic Acid in primary total hip arthroplasty: a randomized double-blind controlled trialJ Arthroplasty. 2014 Dec;29(12):2452-6
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103 patients scheduled for total hip arthroplasty were randomized to intraoperatively receive the application of 3g tranexamic intra-articularly (IA-TXA), or simply receive saline. The purpose of this study was to evaluate the efficacy of IA-TXA in reducing transfusion rate and blood loss, without increasing the incidence of thromboembolic complications. The results demonstrated a significantly lo...
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