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Intra-articular hylastan vs intra-articular steroid in knee OA treatment

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Ace Report Cover
September 2014

Intra-articular hylastan vs intra-articular steroid in knee OA treatment

Vol: 3| Issue: 9| Number:56| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:1

Intra-articular hylastan versus steroid for knee osteoarthritis

Knee Surg Sports Traumatol Arthrosc. 2014 Jul;22(7):1684-92

Contributing Authors:
L Housman N Arden TJ Schnitzer C Birbara T Conrozier N Skrepnik N Wei B Bockow D Waddell H Tahir A Hammond P Goupille BJ Sanson C Elkins F Bailleul

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Synopsis

391 patients with mild-moderate knee osteoarthritis (K-L grade I-III) were randomized to three different intra-articular injection groups: 1x4mL injection of hylastan, 2x4mL injections of hylastan separated by two weeks, or an injection of methylprednisolone acetate 40mg. Patients were followed-up for 26 weeks after the first injection. Pain relief was significant in all three groups after 4 weeks...

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