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Extended-release metoprolol in the prevention of CV complications in non-cardiac surgery
October 2014
Extended-release metoprolol in the prevention of CV complications in non-cardiac surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial
Lancet. 2008 May 31;371(9627):1839-47. doi: 10.1016/S0140-6736(08)60601-7. Epub 2008 May 12.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
9298 patients with, or at risk of, atherosclerotic disease and undergoing non-cardiac surgery, were randomized to receive perioperative administration of either extended-release metoprolol or a placebo equivalent. The purpose of this study was to compare these two groups with respect to rates of cardiovascular complications over a period of 30 postoperative days. Results indicated that, although t...
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