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The effect of bisphosphonates on indirect bone healing

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Ace Report Cover
September 2014

The effect of bisphosphonates on indirect bone healing

Vol: 3| Issue: 9| Number:10| ISSN#: 2564-2537
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Do bisphosphonates affect bone healing? A meta-analysis of randomized controlled trials

J Orthop Surg Res. 2014 Jun 5;9:45

Contributing Authors:
D Xue F Li G Chen S Yan Z Pan

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Synopsis

Data from 8 randomized controlled trials (RCTs) investigating 2,508 patients were pooled to evaluate the effect of bisphosphonates on bone healing. Short- and long-term healing, and delayed fracture and nonunion data were analyzed along with other relevant outcomes. The evidence presented in this meta-analysis indicated that bisphosphonate treatment did not affect short- or long-term healing, dela...

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