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The effect of bisphosphonates on indirect bone healing
September 2014
The effect of bisphosphonates on indirect bone healing
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A
Do bisphosphonates affect bone healing? A meta-analysis of randomized controlled trials
J Orthop Surg Res. 2014 Jun 5;9:45Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
Data from 8 randomized controlled trials (RCTs) investigating 2,508 patients were pooled to evaluate the effect of bisphosphonates on bone healing. Short- and long-term healing, and delayed fracture and nonunion data were analyzed along with other relevant outcomes. The evidence presented in this meta-analysis indicated that bisphosphonate treatment did not affect short- or long-term healing, dela...
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