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Knee OA:Aceclofenac controlled release (200 mg) non-inferior to immediate release (100 mg)
May 2014
Knee OA:Aceclofenac controlled release (200 mg) non-inferior to immediate release (100 mg)
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Efficacy and Safety of Aceclofenac Controlled Release in Patients with Knee Osteoarthritis: A 4-week, Multicenter, Randomized, Comparative Clinical Study
Knee Surg Relat Res. 2014 Mar;26(1):33-42. doi: 10.5792/ksrr.2014.26.1.33Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
125 patients with chronic knee OA were randomized to receive either aceclofenac controlled release (CR) 200 mg oral tablets taken once-daily or aceclofenac immediate release (IR) 100 mg oral tablets taken twice-daily to assess non-inferiority of a lower dosing frequency to a higher one. Results at 4 week post-treatment revealed aceclofenac CR was non-inferior to aceclofenac IR in terms of change i...
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