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RCT
ACE Report #5790
Ace Report Cover Arthroplasty

Tranexamic acid reduces blood loss significantly more than fibrin glue following TKA


Study Type:N/A
OE Level Evidence:2
Journal Level of Evidence:N/A

Efficacy and safety of fibrin glue and tranexamic Acid to prevent postoperative blood loss in total knee arthroplasty: a randomized controlled clinical trial

J Bone Joint Surg Am. 2013 Nov 20;95(22):2001-7

Contributing Authors: X Aguilera MJ Martinez-Zapata A Bosch G Urrútia JC González M Jordan I Gich RM Maymó N Martínez JC Monllau F Celaya JA Fernández

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Synopsis

172 patients who were scheduled for elective primary total knee arthroplasty were randomly assigned into 1 of 4 groups, 2 fibrin glue groups (Blood and Tissue Bank of Batalonia fibrin glue, and Tissucol Duo) 1 tranexamic acid group, and 1 control (receiving routine hemostasis), to determine if fibrin glue or tranexamic acid significantly reduces blood loss following TKA when compared to routine he...

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