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Topical tranexamic acid in TKA effectively reduces blood loss in patients

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Ace Report Cover
November 2013

Topical tranexamic acid in TKA effectively reduces blood loss in patients

Vol: 2| Issue: 10| Number:51| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

A prospective double-blind placebo controlled trial of topical tranexamic Acid in total knee arthroplasty

J Arthroplasty. 2013 Sep;28(8 Suppl):78-82

Contributing Authors:
AG Georgiadis SJ Muh CD Silverton RM Weir MW Laker

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Synopsis

101 patients undergoing primary unilateral TKA were randomly assigned into 1 of 2 groups, an intervention (topical tranexamic acid) or a placebo group, to test the effect of tranexamic acid (TNA) on blood loss and transfusion rates. Results demonstrated that patients who received TKA surgery with tranexamic acid experienced less blood loss than those who were given the placebo. A trend was shown t...

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