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ACE Report #5569
Ace Report Cover Spine

Antibiotic prophylaxis using Cephalosporin in spine surgery

Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Prospective randomized study for antibiotic prophylaxis in spine surgery: choice of drug, dosage, and timing

Asian Spine J. 2013 Sep;7(3):196-203

Contributing Authors: Nishant KK Kailash PV Vijayraghavan

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Dr. Nishant discusses antibiotic prophylaxis in spine surgery.


90 patients who underwent spinal surgery participated in this study to compare the preventative effects of cephalosporin (doses, timing and generation) on infection rates. Patients received 1 g cefazolin (1st generation) or 1 g cefuroxime (2nd generation) or 1.5 g cefuroxime (2nd generation) at different times prior to surgery. 2 out of the 90 patients (2.2%) resulted in infections that were treat...

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