
Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA

March 2013
Tranexamic Acid Reduces Blood Loss and Blood Transfusion after TKA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Tranexamic acid reduces blood loss and blood transfusion after TKA: a prospective randomized controlled trial
Clin Orthop Relat Res. 2011 Oct;469(10):2874-80. Epub 2011 Apr 22Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
100 patients with primary osteoarthritis who were scheduled to undergo unilateral cemented total knee arthroplasty were randomized to receive either placebo or intravenous tranexamic acid 10 minutes prior to surgery, 3 hours after surgery, and orally for 5 days after surgery. Patients who received tranexamic acid displayed significantly less blood loss, hemoglobin loss, and required significantly ...
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