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Tranexamic acid is effective in reducing blood loss, while maintaining safety, in THA

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Ace Report Cover
October 2013

Tranexamic acid is effective in reducing blood loss, while maintaining safety, in THA

Vol: 2| Issue: 9| Number:16| ISSN#: 2564-2537
Study Type:Meta analysis
OE Level Evidence:1
Journal Level of Evidence:N/A

Do we really need tranexamic acid in total hip arthroplasty? A meta-analysis of nineteen randomized controlled trials

Arch Orthop Trauma Surg. 2013 Jul;133(7):1017-27. doi: 10.1007/s00402-013-1761-2. Epub 2013 Apr 25

Contributing Authors:
XD Zhou LJ Tao J Li LD Wu

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Synopsis

19 randomized control trials (n=1,030) evaluating the use of tranexamic acid (TXA) in total hip arthroplasty (THA) procedures were included in this review to investigate the effectiveness of this treatment in the reduction of blood loss. Results indicated that the use of TXA in THA yielded significantly improved total blood loss, intraoperative blood loss volume, postoperative blood loss, "hidden"...

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