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Volume:1 Issue:8 Number:6 ISSN#:2563-5476
Author Verified
RCT
ACE Report #5164
Ace Report Cover Arthroplasty

Extended thromboprophylaxis with aspirin noninferior to dalteparin for THA patients


Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Aspirin versus low-molecular-weight heparin for extended venous thromboembolism prophylaxis after total hip arthroplasty: a randomized trial

Ann Intern Med. 2013 Jun 4;158(11):800-6. doi: 10.7326/0003-4819-158-11-201306040-00004

Contributing Authors: DR Anderson MJ Dunbar ER Bohm E Belzile SR Kahn D Zukor W Fisher W Gofton P Gross S Pelet M Crowther S MacDonald P Kim S Pleasance N Davis P Andreou P Wells M Kovacs MA Rodger T Ramsay M Carrier PA Vendittoli

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Synopsis

786 total hip arthroplasty (THA) patients were administered daily subcutaneous injections containing low-molecular-weight heparin (dalteparin) for 10 days, starting the next morning after surgery. Afterwards, patients were randomized to receive dalteparin injections in combination with placebo aspirin tablets or receive aspirin tablets combined with placebo dalteparin injections for 28 days, to co...

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