Loading...
Visit our Evidence-Based Covid-19 Website and Stay Up to Date with the latest Research.
Author Verified
RCT
ACE Report #5094
Ace Report Cover Tumour

Ifosfamide not necessary in chemotherapy for nonmetastatic osteosarcoma


Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A

Neoadjuvant chemotherapy with methotrexate, cisplatin, and doxorubicin with or without ifosfamide in nonmetastatic osteosarcoma of the extremity: an Italian sarcoma group trial ISG/OS-1

J Clin Oncol. 2012 Jun 10;30(17):2112-8. doi: 10.1200/JCO.2011.38.4420. Epub 2012 May 7

Contributing Authors: S Ferrari P Ruggieri G Cefalo A Tamburini R Capanna F Fagioli A Comandone R Bertulli G Bisogno E Palmerini M Alberghini A Parafioriti A Linari P Picci G Bacci

Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here

Synopsis

246 patients with nonmetastatic osteosarcoma were randomized to evaluate the addition of ifosfamide to a primary chemotherapy regimen of methotrexate, cisplatin, and doxorubicin, with patients allocated to chemotherapy with or without ifosfamide. After a median follow-up of 76 months, there was no difference between groups in overall survival, event-free survival, and the percentage of patients wi...

To view the full report, start your 30-day free trial today

No credit card required

JOIN Forgot Password?

Not sure if you want to join OrthoEvidence?

Access this report without an Account.

Success, an email containing a link to access this report has been sent to your inbox.

CME Image

Continuing Medical Education Credits

You could be earning 0.5 CME credits for each report you read.

LEARN MORE

Please Login or Join to leave comments.