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ACE Report #5011
Ace Report Cover Osteoarthritis

Improvement of condition with hyaluronic acid injection for ankle OA

Study Type:Meta-analysis/Systematic Review
OE Level Evidence:1
Journal Level of Evidence:N/A

Effectiveness of intra-articular hyaluronic acid for ankle osteoarthritis treatment: a systematic review and meta-analysis

Arch Phys Med Rehabil. 2013 May;94(5):951-60. doi: 10.1016/j.apmr.2012.10.030. Epub 2012 Nov 10

Contributing Authors: KV Chang MY Hsiao WS Chen TG Wang KL Chien

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Four randomized controlled trials, 1 double-arm comparative study, and 4 single-arm prospective studies were included in this investigation into the efficacy of hyaluronic acid (HA) injections for ankle osteoarthritis. A total of 354 patients were included throughout the studies. Pooled effect sizes indicated a significantly beneficial effect of HA compared to pre-treatment condition. Comparative ...

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