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Low-dose tranexamic acid does not reduce blood loss or transfusion rate in spinal surgery
November 2013
Low-dose tranexamic acid does not reduce blood loss or transfusion rate in spinal surgery
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A
Efficacy of prophylactic low dose of tranexamic acid in spinal fixation surgery: a randomized clinical trial
J Neurosurg Anesthesiol. 2011 Oct;23(4):290-6. doi: 10.1097/ANA.0b013e31822914a1Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
76 patients scheduled for spinal fixation surgery were randomized to receive prophylactic low-dose tranexamic acid (TXA) or placebo saline to determine the efficacy of TXA on the reduction of perioperative blood loss and blood transfusion. The results indicated that the administration of TXA led to no appreciable blood loss of transfusion reduction compared to saline.
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