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125mg methylprednisolone does not reduce time to meet discharge criteria after THA

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Ace Report Cover
March 2013

125mg methylprednisolone does not reduce time to meet discharge criteria after THA

Vol: 2| Issue: 2| Number:240| ISSN#: 2564-2537
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:N/A

Effect of high-dose preoperative methylprednisolone on recovery after total hip arthroplasty: a randomized, double-blind, placebo-controlled trial

Br J Anaesth. 2013 Jan;110(1):66-73. doi: 10.1093/bja/aes345. Epub 2012 Sep 17

Contributing Authors:
TH Lunn LO Andersen BB Kristensen H Husted L Gaarn-Larsen T Bandholm S Ladelund H Kehlet

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Synopsis

48 patients were randomized to determine the effects of glucocorticoid prophylaxis on the length-to-discharge following total hip arthroplasty. Patients received either a single dose of 125mg methylprednisolone or isotonic saline (placebo) in addition to a multimodal oral analgesic protocol. The results indicated that despite improved immediate post-operative pain and inflammatory response, there ...

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