Vitamin D supplementation has no major impact on knee OA symptoms or progression
Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: a randomized controlled trialJAMA. 2013 Jan 9;309(2):155-62. doi: 10.1001/jama.2012.164487
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146 patients were randomized to evaluate the effect of vitamin D supplementation on the symptoms and structural progression of knee osteoarthritis (OA). Patients with knee OA received either placebo or oral cholecalciferol (2000 IU/d) and were assessed after 2 years. Results revealed that vitamin D supplementation for 2 years did not reduce knee pain or cartilage volume loss in comparison to the p...
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