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IV magnesium sulphate does not increase CSF Mg levels in spinal anaesthesia patients
August 2013
IV magnesium sulphate does not increase CSF Mg levels in spinal anaesthesia patients
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Changes in cerebrospinal fluid magnesium levels in patients undergoing spinal anaesthesia for hip arthroplasty: does intravenous infusion of magnesium sulphate make any difference? A prospective, randomized, controlled study
Br J Anaesth. 2012 Aug;109(2):208-15. doi: 10.1093/bja/aes146. Epub 2012 Jun 1Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
45 neurologically healthy patients undergoing continuous spinal anaesthesia for hip arthroplasty were randomized to receive intravenous magnesium sulphate (MgSO4) or saline. Over 6 hours, the magnesium concentration in the serum increased in the MgSO4 group and decreased in the saline group. However, both groups demonstrated a decrease in the cerebrospinal fluid (CSF) magnesium concentration at 2 ...
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