Intra-articular injection of S(+)- ketamine does not reduce pain after TKA
Analgesic Efficacy of the Intra-articular Administration of S(+)- Ketamine in Patients Undergoing Total Knee ArthroplastyRev Bras Anestesiol. 2012 Sep;62(5):665-75. doi: 10.1016/S0034-7094(12)70165-4
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60 patients undergoing total knee arthroplasty (TKA) were randomized to one of three groups to examine the effects of S(+)- ketamine on postoperative pain. Patients were randomized to receive intra-articular injections of 0.25 mg.kg of S(+)- ketamine diluted in 20 mL of saline solution 0.9% (group A), 0.5 mg.kg of S(+)- ketamine diluted in 20 mL of saline solution 0.9% (group B), or 20 mL of intra...
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