OTA: Indomethacin is no better than placebo for preventing heterotopic ossification
Incidence of Posterior Wall Nonunion and Efficacy of Indomethacin Prophylaxis for Heterotopic Ossification After Operative Fixation of Acetabular Fractures: A Randomized Controlled Trial
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98 patients with an acetabular fracture were included in a study to examine the effects of indomethacin on the prevention of heterotopic ossification (HO). Patients underwent open reduction and internal fixation through a Kocher-Langenbeck approach. They were then randomized to receive placebo for 6 weeks (group 1), 3 days of indomethacin followed by placebo for a total of 6 weeks (group 2), 1 wee...
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