Perioperative administration of celecoxib reduces opioid consumption
Analgesic Efficacy of Perioperative Celecoxib in Ambulatory Arthroscopic Knee Surgery: A Double-Blind, Placebo-Controlled StudyArthroscopy. 2006 Jun;22(6):635-42.
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166 patients with knee meniscus disease who were undergoing ambulatory arthroscopic knee meniscectomy were included in a study to test the effects of preoperatively administered celecoxib compared to a placebo. Patients in the experimental group were administered 400 mg of celecoxib 1 hour before surgery, and 200 mg of celecoxib at their first request post-operation. The control group received pla...
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