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Preoperative human recombinant erythropoietin reduces allogenic blood transfusion
May 2013
Preoperative human recombinant erythropoietin reduces allogenic blood transfusion
Study Type:Therapy
OE Level Evidence:2
Journal Level of Evidence:N/A
Two different dosing regimens of human recombinant erythropoietin beta during preoperative autologous blood donation in patients having hip arthroplasty.
Int Orthop. 2012 Apr;36(4):703-9. Epub 2011 Oct 1.Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
93 patients undergoing total hip arthroplasty were randomized to differing preoperative dosing regimes of human recombinant erythropoietin (rHu-EPO) to elucidate its affect on preoperative blood donation and intra-operative blood transfusions. Patients received either a once weekly i.v of 30000 IU rHu-EPO, a twice weekly i.v. of 15000 IU rHu-EPO, or no rHu-EPO. All groups received an oral does of ...
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