
Zoledronic acid reduces early implant migration in total hip arthroplasty

Zoledronic acid reduces early implant migration in total hip arthroplasty
The effect of a single infusion of zoledronic acid on early implant migration in total hip arthroplasty. A randomized, double-blind, controlled trial
J Bone Joint Surg Am. 2009 Feb;91(2):274-81Did you know you're eligible to earn 0.5 CME credits for reading this report? Click Here
Synopsis
50 patients with osteonecrosis of the femoral head, scheduled for total hip arthroplasty (THA), were randomized to receive a post-operative injection of zoledronic acid or saline. This trial assessed the effect of zoledronic acid on early implant migration, which was associated with aspect loosening in THA. After a 2 year follow-up, radiographic results indicated a reduction in acetabular componen...
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