Zoledronic acid reduces early implant migration in total hip arthroplasty
The effect of a single infusion of zoledronic acid on early implant migration in total hip arthroplasty. A randomized, double-blind, controlled trialJ Bone Joint Surg Am. 2009 Feb;91(2):274-81
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50 patients with osteonecrosis of the femoral head, scheduled for total hip arthroplasty (THA), were randomized to receive a post-operative injection of zoledronic acid or saline. This trial assessed the effect of zoledronic acid on early implant migration, which was associated with aspect loosening in THA. After a 2 year follow-up, radiographic results indicated a reduction in acetabular componen...
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