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Intravenous Carbazochrome Enhances Visual Clarity and Efficiency in Arthroscopic Rotator Cuff Repair
November 2025
Intravenous Carbazochrome Enhances Visual Clarity and Efficiency in Arthroscopic Rotator Cuff Repair
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Preoperative Intravenous Carbazochrome Sodium Sulfonate Improves Visual Clarity in Patients Undergoing Arthroscopic Rotator Cuff Repair Compared to Tranexamic Acid and Sodium Chloride: A Randomized Controlled, Triple-Blinded, Prospective Study.
Arthroscopy . 2025 Aug;41(8):2795-2804.Synopsis
One hundred ninety-five patients with rotator cuff tears undergoing arthroscopic double-row repair were randomized to receive carbazochrome sodium sulfonate (CSS) 80 mg IV (n=65), Tranexamic acid (TXA) 100 mg IV (n=65), or 0.9% sodium chloride 60 mg IV (n=65), administered five minutes pre-incision and again three hours post-op via light-protected infusion (triple-blind). The primary outcome was i...
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