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Analgesic Application Of A Novel Non-Steroidal Anti-Inflammatory Drug Imrecoxib After TKA
November 2025
Analgesic Application Of A Novel Non-Steroidal Anti-Inflammatory Drug Imrecoxib After TKA
Study Type:Therapy
OE Level Evidence:1
Journal Level of Evidence:1
Analgesic application of a novel non-steroidal anti-inflammatory drug imrecoxib after total knee arthroplasty: a prospective randomized controlled study.
Perioper Med (Lond) . 2025 Jul 15;14(1):73.Synopsis
One hundred twenty patients with end-stage knee osteoarthritis scheduled for primary TKA were randomized 1:1 to imrecoxib added to conventional care (n=60) or conventional care alone (n=60). The primary outcome was pain (VAS at 6, 12, 24, 48 h). Secondary outcomes included knee ROM at 24/48 h, in-hospital opioid consumption (tablets), inflammatory markers (ESR, CRP, IL-6) at 24/48 h, and adverse e...
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